SCHEMBL2734583

SCHEMBL2734583

Oc1c(-c2ccccn2)cccc1-c1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.56
LMNA P02545 3/20 0.56
CCR1 P32246 2/20 0.56
CCR5 P51681 2/20 0.56
CCR8 P51685 2/20 0.56
CYP1A2 P05177 1/20 0.56
POLB P06746 1/20 0.56
METAP1 P53582 1/20 0.56
BLM P54132 1/20 0.56
HIF1A Q16665 1/20 0.56
DOHH Q9BU89 1/20 0.56
P4HTM Q9NXG6 1/20 0.56
TP53 P04637 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
ALOX15 P16050 2/20 0.54
HTT P42858 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
MAPK1 P28482 2/20 0.54
ALPL P05186 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30336107 0.91 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL16800591 0.90 TGFBR1 (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5463849 0.90 KDM4E (0.50) KDM4ELMNACCR1CCR5CCR8
SCHEMBL19830918 0.88 KDM4E (0.69) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30834987 0.88 KDM4E (0.69) KDM4ELMNACCR1CCR5CCR8
SCHEMBL16627984 0.86 SMN1; SMN2 (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7718810 0.86 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7205198 0.85 KDM4E (0.45) KDM4ELMNACCR1CCR5CCR8
SCHEMBL27924279 0.83 KDM4E (0.65) KDM4ELMNACCR1CCR5CCR8
SCHEMBL13580667 0.83 KDM4E (0.43) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2568515-B1 OLED device with fluoranthene electron transport materials GLOBAL OLED TECHNOLOGY LLC (US) 2016-02-24 EP disclosed
EP-2240465-B1 NOVEL PHENOL COMPOUNDS AND (CO)POLYMERS THEREOF SIKKEMA DOETZE JAKOB (NL) 2015-10-14 EP disclosed
US-8519131-B2 Modified metal complex and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-27 US disclosed
US-8519131-B2 Modified metal complex and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-08-27 US disclosed
US-8431242-B2 OLED device with certain fluoranthene host GLOBAL OLED TECHNOLOGY, LLC. (US) 2013-04-30 US disclosed
US-8431242-B2 OLED device with certain fluoranthene host GLOBAL OLED TECHNOLOGY, LLC. (US) 2013-04-30 US disclosed
US-8420229-B2 OLED device with certain fluoranthene light-emitting dopants Global OLED Technologies LLC (US) 2013-04-16 US disclosed
US-8420229-B2 OLED device with certain fluoranthene light-emitting dopants Global OLED Technologies LLC (US) 2013-04-16 US disclosed
EP-2568515-A1 OLED device with fluoranthene electron transport materials Global OLED Technology LLC (US) 2013-03-13 EP disclosed
US-8216697-B2 OLED with fluoranthene-macrocyclic materials GLOBAL OLED TECHNOLOGY LLC (US) 2012-07-10 US disclosed
US-20100105909-A1 MODIFIED METAL COMPLEX AND USE THEREOF SUMITTO CHEMICAL COMPANY, LIMITED (JP) 2010-04-29 US disclosed
US-20100105909-A1 MODIFIED METAL COMPLEX AND USE THEREOF SUMITTO CHEMICAL COMPANY, LIMITED (JP) 2010-04-29 US disclosed
WO-2009097084-A1 TANDEM OLED DEVICE WITH INTERMEDIATE CONNECTOR EASTMAN KODAK COMPANY (US) 2009-08-06 WO disclosed
US-20090195146-A1 TANDEM OLED DEVICE WITH INTERMEDIATE CONNECTOR GLOBAL OLED TECHNOLOGY LLC 2009-08-06 US disclosed
US-20090191428-A1 TANDEM OLED DEVICE WITH INTERMEDIATE CONNECTOR GLOBAL OLED TECHNOLOGY LLC 2009-07-30 US disclosed
US-20090110956-A1 OLED DEVICE WITH ELECTRON TRANSPORT MATERIAL COMBINATION GLOBAL OLED TECHNOLOGY LLC 2009-04-30 US disclosed
US-20090108735-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON TRANSPORT MATERIALS GLOBAL OLED TECHNOLOGY LLC 2009-04-30 US disclosed
US-20090110957-A1 OLED DEVICE WITH CERTAIN FLUORANTHENE HOST GLOBAL OLED TECHNOLOGY LLC 2009-04-30 US disclosed
US-20090108734-A1 OLED DEVICE WITH CERTAIN FLUORANTHENE LIGHT-EMITTING DOPANTS GLOBAL OLED TECHNOLOGY LLC 2009-04-30 US disclosed
WO-2009054905-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON TRANSPORT MATERIALS EASTMAN KODAK COMPANY (US) 2009-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100105909-A1 MODIFIED METAL COMPLEX AND USE THEREOF TPR, MT-CO2, AP3M1 KDM4E 2512/4885LMNA 3410/4885CCR1 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.