Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16801069 | 0.90 | CYP19A1 (0.36) | CYP19A1GRM5 | |
| SCHEMBL16799620 | 0.85 | SLC6A4 (0.31) | GRM5 | |
| SCHEMBL16800838 | 0.84 | SLC6A4 (0.34) | GRM5 | |
| SCHEMBL16800691 | 0.83 | GRM5 (0.30) | GRM5 | |
| SCHEMBL16799452 | 0.79 | — | — | |
| SCHEMBL16798942 | 0.78 | GRM5 (0.37) | GRM5 | |
| SCHEMBL30646147 | 0.76 | GRM5 (0.36) | GRM5 | |
| SCHEMBL16800873 | 0.75 | RORC (0.56) | — | |
| SCHEMBL30646121 | 0.72 | GRM5 (0.39) | GRM5 | |
| SCHEMBL31668777 | 0.71 | GRM5 (0.36) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015083130-A1 | FUSED PYRIDINE AND PYRIMIDINE DERIVATIVES AS ROR GAMMA MODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-06-11 | — | — | WO | disclosed |