Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTR1D | P28221 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.47 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.45 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865138 | 0.82 | HTR2C (0.61) | HTR2CKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL6203684 | 0.80 | HTR2C (0.61) | HTR2CKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL654975 | 0.80 | HTR2C (0.61) | HTR2CKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL25293469 | 0.79 | HTR2A (0.65) | HTR2CKDM4EALDH1A1HTR6CCNT1 | |
| SCHEMBL6629475 | 0.79 | ALDH1A1 (0.57) | HTR2CKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL10557861 | 0.79 | HTR2A (0.65) | HTR2CKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL614978 | 0.77 | CCNT1 (0.57) | HTR2CKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL31348179 | 0.77 | CCNT1 (0.57) | HTR2CKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL7864873 | 0.76 | HTR2C (0.57) | HTR2CKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL4366189 | 0.75 | CCNT1 (0.46) | HTR2CKDM4EALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015082499-A2 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD (GB) | 2015-06-11 | — | — | WO | disclosed |