SCHEMBL16802139

SCHEMBL16802139

CC1(C)c2ccccc2-c2c(-c3ccc(N(c4ccc(-c5cccc6c5-c5ccccc5C6(C)C)cc4)c4ccc(-c5cccc6c5oc5ccccc56)cc4)cc3)cccc21

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.44
GGPS1 O95749 1/20 0.34
PRKDC P78527 5/20 0.34
MEN1 O00255 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
PGR P06401 1/20 0.34
PTGES2 Q9H7Z7 1/20 0.32
TNKS O95271 1/20 0.31
PIK3CD O00329 1/20 0.31
PIK3CB P42338 1/20 0.31
ALK Q9UM73 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22402033 1.00 ALOX5 (0.44) ALOX5GGPS1PRKDCMEN1CYP2C19
SCHEMBL16858178 0.97 ALOX5 (0.42) ALOX5GGPS1PRKDCMEN1CYP2C19
SCHEMBL23376055 0.94 ALOX5 (0.42) ALOX5GGPS1PRKDCMEN1CYP2C19
SCHEMBL16802227 0.94 ALOX5 (0.42) ALOX5GGPS1PRKDCMEN1CYP2C19
SCHEMBL24155998 0.94 ALOX5 (0.45) ALOX5GGPS1PRKDCMEN1CYP2C19
SCHEMBL22402040 0.92 ALOX5 (0.43) ALOX5GGPS1PRKDCMEN1CYP2C19
SCHEMBL10108432 0.92 ALOX5 (0.42) ALOX5GGPS1PRKDCMEN1CYP2C19
SCHEMBL16858158 0.92 ALOX5 (0.43) ALOX5GGPS1PRKDCMEN1CYP2C19
SCHEMBL16801888 0.92 ALOX5 (0.38) ALOX5PRKDCMEN1CYP2C19KMT2A
SCHEMBL22480603 0.92 ALOX5 (0.41) ALOX5GGPS1PRKDCPTGES2ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220246856-A1 LIGHT-EMITTING DIODE AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-08-04 US disclosed
US-11056652-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2021-07-06 US disclosed
EP-3693437-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES Merck Patent GmbH (DE) 2020-08-12 EP disclosed
US-20190288209-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-09-19 US disclosed
US-10355217-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2019-07-16 US disclosed
EP-3345984-A1 CONNECTIONS AND ORGANIC ELECTRONIC DEVICES Merck Patent GmbH (DE) 2018-07-11 EP disclosed
EP-3077477-B1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-02-28 EP disclosed
US-20170194569-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194569-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170186969-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed
US-20170186969-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed
US-20170186978-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed
US-20170186978-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-29 US disclosed
US-20160301005-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-10-13 US disclosed
US-20160301005-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-10-13 US disclosed
WO-2015082056-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10355217-B2 Compounds and organic electronic devices ETV6, AFF2, CYP2C19 ALOX5 953/4885GGPS1 576/4885PRKDC 1300/4885
US-11056652-B2 Compounds and organic electronic devices ETV6, AFF2, CYP2C19 ALOX5 953/4885GGPS1 576/4885PRKDC 1300/4885
US-20190288209-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, AFF2, CYP2C19 ALOX5 953/4885GGPS1 576/4885PRKDC 1300/4885
US-20160301005-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, AFF2, CYP2C19 ALOX5 953/4885GGPS1 576/4885PRKDC 1300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.