Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16802139 | 1.00 | ALOX5 (0.44) | ALOX5GGPS1PRKDCMEN1CYP2C19 | |
| SCHEMBL16858178 | 0.97 | ALOX5 (0.42) | ALOX5GGPS1PRKDCMEN1CYP2C19 | |
| SCHEMBL23376055 | 0.94 | ALOX5 (0.42) | ALOX5GGPS1PRKDCMEN1CYP2C19 | |
| SCHEMBL16802227 | 0.94 | ALOX5 (0.42) | ALOX5GGPS1PRKDCMEN1CYP2C19 | |
| SCHEMBL24155998 | 0.94 | ALOX5 (0.45) | ALOX5GGPS1PRKDCMEN1CYP2C19 | |
| SCHEMBL22402040 | 0.92 | ALOX5 (0.43) | ALOX5GGPS1PRKDCMEN1CYP2C19 | |
| SCHEMBL10108432 | 0.92 | ALOX5 (0.42) | ALOX5GGPS1PRKDCMEN1CYP2C19 | |
| SCHEMBL16858158 | 0.92 | ALOX5 (0.43) | ALOX5GGPS1PRKDCMEN1CYP2C19 | |
| SCHEMBL16801888 | 0.92 | ALOX5 (0.38) | ALOX5PRKDCMEN1CYP2C19KMT2A | |
| SCHEMBL22480603 | 0.92 | ALOX5 (0.41) | ALOX5GGPS1PRKDCPTGES2ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200283386-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283386-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, GPX1, SOD1 | ALOX5 3274/4885GGPS1 1659/4885PRKDC 2727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.