Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842100 | 0.83 | CDC7 (0.44) | LMNAALOX5RAB9ANPC1ALDH1A1 | |
| SCHEMBL12278149 | 0.81 | CYP3A4 (0.60) | CYP3A4CYP1A2LMNACYP2C19ALOX5 | |
| SCHEMBL14636146 | 0.81 | ALOX5 (0.44) | LMNAALOX5RAB9ANPC1CYP2A6 | |
| SCHEMBL12277978 | 0.79 | KDM4E (0.54) | CYP3A4CYP1A2LMNAALOX5RAB9A | |
| SCHEMBL12279088 | 0.78 | CYP3A4 (0.51) | CYP3A4CYP1A2LMNACYP2C19ALOX5 | |
| SCHEMBL12279371 | 0.78 | CYP19A1 (0.66) | CYP3A4LMNARAB9ANPC1CYP2C9 | |
| SCHEMBL12279174 | 0.77 | CYP19A1 (0.52) | CYP3A4CYP1A2LMNACYP2C19ALOX5 | |
| SCHEMBL1679855 | 0.76 | CYP3A4 (0.49) | CYP3A4CYP1A2LMNACYP2C19ALOX5 | |
| SCHEMBL1679661 | 0.76 | CYP3A4 (0.49) | CYP3A4CYP1A2LMNACYP2C19ALOX5 | |
| SCHEMBL1679841 | 0.75 | CYP3A4 (0.48) | CYP3A4CYP1A2LMNACYP2C19ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9451775-B2 | Heterocyclic compounds as pesticides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| EP-2583556-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-01-20 | — | — | EP | disclosed |
| EP-2583556-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-01-20 | — | — | EP | disclosed |
| EP-2591674-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-01-13 | — | — | EP | disclosed |
| EP-2591674-B1 | Heterocyclic compounds as pest controllers | BAYER CROPSCIENCE AG (DE) | 2016-01-13 | — | — | EP | disclosed |
| CN-104642337-A | Heterocyclic Compounds Used As Pesticides | BAYER CROPSCIENCE AG | 2015-05-27 | — | — | CN | disclosed |
| CN-102159079-B | Heterocyclic compounds useful as pesticides | BAYER CROPSCIENCE AG | 2015-02-18 | — | — | CN | disclosed |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | BAYER CORPSCIENCE AG (DE) | 2014-11-13 | — | — | US | disclosed |
| EP-2583556-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583557-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| EP-2583557-A1 | Heterocyclic compounds as pest controllers | Bayer CropScience AG (DE) | 2013-04-24 | — | — | EP | disclosed |
| WO-2013010947-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS II | BASF SE (DE) | 2013-01-24 | — | — | WO | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG | 2011-09-01 | — | — | US | disclosed |
| EP-2309857-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010006713-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010006713-A2 | HETEROCYCLIC COMPOUNDS USED AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212949-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | CYP3A4 72/4885CYP1A2 73/4885LMNA 2126/4885 |
| US-20140336186-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | CYP3A4 72/4885CYP1A2 73/4885LMNA 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.