Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 14/20 | 0.37 |
| ▸ | PGR | P06401 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291983 | 0.81 | NR3C1 (0.31) | NR3C1PGRNR3C2 | |
| SCHEMBL291171 | 0.79 | NR3C1 (0.40) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL292426 | 0.72 | NR3C1 (0.57) | NR3C1PGRCYP3A4NR3C2KCNH2 | |
| SCHEMBL1680219 | 0.71 | NR3C1 (0.48) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL291016 | 0.70 | NR3C1 (0.55) | NR3C1PGRNR3C2 | |
| SCHEMBL291200 | 0.69 | CYP11B1 (0.44) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL5396225 | 0.67 | KCNH2 (0.32) | NR3C1PGRNR3C2KCNH2 | |
| SCHEMBL292068 | 0.65 | NR3C1 (0.59) | NR3C1PGRNR3C2 | |
| SCHEMBL5781547 | 0.64 | NR3C1 (0.56) | NR3C1PGRCYP3A4NR3C2 | |
| SCHEMBL448531 | 0.63 | DDAH1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061444-B1 | COMPOSITIONS AND METHODS FOR TREATING, CONTROLLING, REDUCING, AMELIORATING, OR PREVENTING ALLERGY | BAUSCH & LOMB (US) | 2011-04-20 | — | — | EP | disclosed |