Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330128 | 0.90 | MAPT (0.54) | MAPTKMT2AMEN1LMNAATM | |
| SCHEMBL10330604 | 0.86 | MAPT (0.57) | MAPTKMT2AMEN1LMNAATM | |
| SCHEMBL10695262 | 0.77 | MAPT (0.49) | MAPTKMT2AMEN1LMNAATM | |
| SCHEMBL16802880 | 0.74 | MAPT (0.46) | MAPTKMT2AMEN1LMNAATM | |
| SCHEMBL28599104 | 0.73 | POLB (0.61) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL7523145 | 0.73 | EPHX2 (0.51) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL13411694 | 0.72 | MAPT (0.59) | MAPTKMT2AMEN1LMNAATM | |
| SCHEMBL2330120 | 0.72 | CA12 (0.56) | MAPTKMT2AMEN1LMNANPC1 | |
| SCHEMBL12808274 | 0.72 | POLB (0.44) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL18063667 | 0.71 | MAPT (0.58) | MAPTKMT2AMEN1LMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483324-B1 | METHOD FOR LOWERING EMISSIONS OF A POLYURETHANE FOAM | BAYER IP GMBH (DE) | 2015-06-17 | — | — | EP | disclosed |