Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602991 | 0.82 | ALDH1A1 (0.49) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28599104 | 0.80 | POLB (0.61) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10330604 | 0.77 | MAPT (0.57) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7528507 | 0.76 | SMN1; SMN2 (0.67) | ALDH1A1RAB9ANPC1SMN1; SMN2ALOX15 | |
| SCHEMBL10330128 | 0.73 | MAPT (0.54) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28244653 | 0.72 | ALDH1A1 (0.44) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16802910 | 0.72 | MAPT (0.46) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14448170 | 0.71 | ALDH1A1 (0.44) | POLBALDH1A1SMN1; SMN2ALOX15MEN1 | |
| SCHEMBL11320359 | 0.71 | GNG2 (0.53) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6827238 | 0.70 | KDM4E (0.68) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038846-A1 | METHOD FOR LOWERING EMISSIONS OF A POLYURETHANE FOAM | BAYER MATERIALSCIENCE AG (DE) | 2011-04-07 | — | — | WO | disclosed |