SCHEMBL1680314

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680862	0.92	MAPK8 (0.35)	MAPK8LOXLOXL2KLKB1MAPK14
	SCHEMBL1680895	0.91	CCNA2 (0.38)	MAPK8KLKB1GALR3NR2F2ALDH1A1
	SCHEMBL1680984	0.89	MAPK8 (0.35)	MAPK8LOXLOXL2KLKB1MAPK14
	SCHEMBL1681018	0.89	MAPK8 (0.42)	MAPK8MAPK14GALR3NR2F2ALDH1A1
	SCHEMBL1681063	0.89	CCNA2 (0.36)	MAPK8LOXLOXL2KLKB1MAPK14
	SCHEMBL2313169	0.89	KLKB1 (0.33)	MAPK8KLKB1MAPK14GALR3NR2F2
	SCHEMBL1681144	0.88	PPARG (0.36)	MAPK8LOXL2KLKB1ALDH1A1HPGD
	SCHEMBL1681061	0.88	MAPK8 (0.33)	MAPK8LOXLOXL2KLKB1MAPK14
	SCHEMBL1680840	0.87	KLKB1 (0.39)	MAPK8KLKB1MAPK14GALR3NR2F2
	SCHEMBL1681209	0.87	MAPK14 (0.44)	MAPK8MAPK14ALDH1A1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.