SCHEMBL1680332

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1680719	0.83	AR (0.49)	SLC22A12FNTAFNTBPGGT1BCNR1
	SCHEMBL1680588	0.83	AR (0.49)	MRGPRX1ALDH1A1PTGS1PTGS2GCK
	SCHEMBL1680570	0.83	FNTA (0.36)	FNTAFNTBPGGT1BMAPTALDH1A1
	SCHEMBL1106848	0.81	TSHR (0.41)	MAPTKDM4EALDH1A1HPGD
	SCHEMBL921181	0.80	POLB (0.47)	MAPTKDM4EALDH1A1
	SCHEMBL12943536	0.80	GUSB (0.33)	MAPTALDH1A1HPGD
	SCHEMBL510507	0.80	GAA (0.43)	SLC22A12MRGPRX1MMP2MMP9MMP14
	SCHEMBL5697493	0.77	MRGPRX1 (0.45)	MRGPRX1MMP2MMP3MMP9MMP14
	SCHEMBL5697491	0.77	MRGPRX1 (0.39)	MRGPRX1MMP2MMP3MMP9MMP14
	SCHEMBL1680567	0.76	MAOB (0.49)	KDM4EALDH1A1CDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.