Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCAT | P04180 | 8/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 10/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16648673 | 0.77 | LCAT (0.72) | LCAT | |
| SCHEMBL16948816 | 0.77 | LCAT (0.56) | LCAT | |
| SCHEMBL16948831 | 0.71 | LCAT (0.56) | LCAT | |
| SCHEMBL16948785 | 0.71 | LCAT (0.51) | LCAT | |
| SCHEMBL16648763 | 0.70 | LCAT (0.55) | LCAT | |
| SCHEMBL16803493 | 0.69 | LCAT (0.45) | LCATCXCR3 | |
| SCHEMBL19485091 | 0.69 | LCAT (0.63) | LCAT | |
| SCHEMBL25075358 | 0.68 | LCAT (0.41) | LCATCXCR3TIPARP | |
| SCHEMBL18138646 | 0.67 | LCAT (0.75) | LCAT | |
| SCHEMBL18138551 | 0.67 | LCAT (0.75) | LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015111545-A1 | CONDENSED PYRAZOLE DERIVATIVE | 第一三共株式会社 | 2015-07-30 | — | — | WO | disclosed |