SCHEMBL1680408

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2515837	0.89	TAAR1 (0.54)	TAAR1HTR2APOLBCTDSP1IDO1
	SCHEMBL11104424	0.88	MAPK1 (0.47)	TAAR1HTR2APOLBCTDSP1MAPK1
	SCHEMBL11108664	0.85	TAAR1 (0.47)	TAAR1HTR2APOLBCTDSP1ALDH1A1
	SCHEMBL18857101	0.85	TAAR1 (0.46)	TAAR1MAPK1SMN1; SMN2LMNAALDH1A1
	SCHEMBL8417751	0.83	TAAR1 (0.45)	TAAR1HTR2APOLBCTDSP1SMN1; SMN2
	SCHEMBL8418497	0.81	IDO1 (0.50)	TAAR1HTR2APOLBCTDSP1LMNA
	SCHEMBL6229666	0.81	CA1 (0.42)	TAAR1LMNAALDH1A1CASP1IDO1
	SCHEMBL12299452	0.81	KCNH2 (0.53)	TAAR1IDO1CYP1A2KCNH2
	SCHEMBL6123807	0.80	TAAR1 (0.52)	TAAR1MAPK1SMN1; SMN2LMNAALDH1A1
	SCHEMBL7931860	0.80	TAAR1 (0.42)	TAAR1HTR2APOLBCTDSP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.