SCHEMBL16804103

SCHEMBL16804103

c1ccc(-n2c3ccccc3c3cc(-c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6oc7ccc(-n8c9ccccc9c9ccccc98)cc7c6c5)cc4)ccc32)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 1/20 0.50
HDAC4 P56524 1/20 0.39
PLA2G2A P14555 3/20 0.39
PLA2G4A P47712 3/20 0.39
EDNRB P24530 1/20 0.37
EDNRA P25101 1/20 0.37
TSPO P30536 1/20 0.36
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
ALDH1A1 P00352 3/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.35
BRCA1 P38398 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTGER4 P35408 1/20 0.35
PLA2G10 O15496 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18975409 1.00 KDM4E (0.50) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL22461714 0.99 L3MBTL1 (0.49) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL10331648 0.99 L3MBTL1 (0.49) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL18266013 0.99 L3MBTL1 (0.49) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL15625340 0.99 L3MBTL1 (0.49) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL14849213 0.99 L3MBTL1 (0.49) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL18266067 0.99 L3MBTL1 (0.49) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL10348853 0.99 KDM4E (0.51) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL5028236 0.99 KDM4E (0.51) KDM4EL3MBTL1ATMHDAC4PLA2G2A
SCHEMBL10331649 0.99 KDM4E (0.51) KDM4EL3MBTL1ATMHDAC4PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150166515-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US disclosed
US-20150166515-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166515-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME LEF1, ELAVL1, OR10J3 KDM4E 2262/4885L3MBTL1 648/4885ATM 2604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.