Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16804661 | 0.91 | PLA2G4B (0.55) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL40246 | 0.89 | CYP4F2 (0.49) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL25284732 | 0.88 | MRGPRX4 (0.56) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL40891 | 0.85 | MRGPRX4 (0.43) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL15444416 | 0.85 | KDM4E (0.48) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL27487853 | 0.83 | CYP4F2 (0.47) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL27865824 | 0.82 | CYP4F2 (0.57) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL40890 | 0.81 | MRGPRX4 (0.43) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL40158 | 0.81 | CYP4F2 (0.41) | MRGPRX4CYP4F2CYP4A11TP53PKM | |
| SCHEMBL40210 | 0.81 | CYP4F2 (0.41) | MRGPRX4CYP4F2CYP4A11TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150164876-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2015-06-18 | — | — | US | disclosed |
| US-20150164876-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150164876-A1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | SLC34A2, SLC34A1, SLC10A2 | MRGPRX4 947/4885CYP4F2 316/4885CYP4A11 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.