SCHEMBL16805652

SCHEMBL16805652

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc5c(c4)c4ccccc4n5-c4cccc(-c5ccc6oc7ccccc7c6c5)c4)c3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.39
PLA2G4A P47712 4/20 0.39
PLA2G10 O15496 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CHEK2 O96017 1/20 0.37
PTGER4 P35408 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPSE Q9Y251 2/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
PRKDC P78527 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15786062 1.00 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL24302119 0.99 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL20715061 0.99 KDM4E (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL12455158 0.99 KDM4E (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL15786114 0.98 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL15785911 0.98 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL19845459 0.98 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL24352756 0.98 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL24303749 0.98 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10KDM4EATM
SCHEMBL24303285 0.98 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9812653-B2 Carbazole compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-07 US disclosed
US-9812653-B2 Carbazole compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-07 US disclosed
US-20150171342-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-06-18 US disclosed
US-20150171342-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150171342-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 PLA2G2A 4722/4885PLA2G4A 4661/4885PLA2G10 4773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.