SCHEMBL16805682

SCHEMBL16805682

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c4c4ccccc4n5-c4cccc(-c5ccc6c(c5)oc5ccccc56)c4)c3)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.34
PRKDC P78527 1/20 0.33
ALOX5 P09917 1/20 0.33
PDE10A Q9Y233 1/20 0.32
PTGER4 P35408 1/20 0.32
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
TP53 P04637 1/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
PLA2G10 O15496 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HPSE Q9Y251 1/20 0.31
AHR P35869 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21128929 0.97 HCRTR1 (0.34) HCRTR1PDE10APTGER4MMP12MMP13
SCHEMBL21964371 0.97 HCRTR1 (0.35) HCRTR1PRKDCALOX5PTGER4MMP12
SCHEMBL21129105 0.96 HCRTR1 (0.34) HCRTR1PRKDCPDE10APTGER4MMP12
SCHEMBL21964384 0.96 MAPT (0.34) HCRTR1PRKDCALOX5PDE10APTGER4
SCHEMBL21863088 0.96 KDM4E (0.35) HCRTR1PRKDCALOX5PTGER4KDM4E
SCHEMBL21128957 0.95 MAPT (0.33) HCRTR1PRKDCALOX5PDE10APTGER4
SCHEMBL21964875 0.95 HCRTR1 (0.35) HCRTR1PRKDCALOX5PTGER4MMP12
SCHEMBL21192083 0.95 HCRTR1 (0.35) HCRTR1PRKDCALOX5PTGER4MMP12
SCHEMBL21192250 0.95 KDM4E (0.36) HCRTR1PRKDCALOX5PTGER4KDM4E
SCHEMBL21964874 0.95 KDM4E (0.36) HCRTR1PRKDCALOX5PTGER4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9812653-B2 Carbazole compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-07 US disclosed
US-9812653-B2 Carbazole compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-07 US disclosed
US-20150171342-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-06-18 US disclosed
US-20150171342-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG SDI CO., LTD. (KR) 2015-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150171342-A1 CARBAZOLE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 HCRTR1 263/4885PRKDC 2787/4885ALOX5 707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.