SCHEMBL21964384

SCHEMBL21964384

c1ccc(-c2nc(-c3cccc(-n4c5ccccc5c5c(-c6ccccc6)cccc54)c3)nc(-c3ccc4c(c3)oc3ccccc34)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.34
HCRTR1 O43613 1/20 0.33
PTGER4 P35408 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TP53 P04637 1/20 0.33
KDM4E B2RXH2 3/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PRKDC P78527 1/20 0.32
AHR P35869 1/20 0.32
ALOX5 P09917 1/20 0.32
BACE1 P56817 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
PDE10A Q9Y233 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21128957 0.99 MAPT (0.33) MAPTHCRTR1PTGER4NPSR1TP53
SCHEMBL21129105 0.98 HCRTR1 (0.34) MAPTHCRTR1PTGER4NPSR1TP53
SCHEMBL21128929 0.97 HCRTR1 (0.34) MAPTHCRTR1PTGER4NPSR1TP53
SCHEMBL16805682 0.96 HCRTR1 (0.34) MAPTHCRTR1PTGER4TP53KDM4E
SCHEMBL21583540 0.96 BACE1 (0.33) MAPTHCRTR1NPSR1TP53KDM4E
SCHEMBL27333142 0.95 PTGER4 (0.36) MAPTHCRTR1PTGER4NPSR1KDM4E
SCHEMBL21192250 0.95 KDM4E (0.36) MAPTHCRTR1PTGER4KDM4EATM
SCHEMBL26451263 0.94 HCRTR1 (0.34) MAPTHCRTR1PTGER4TP53KDM4E
SCHEMBL21863088 0.94 KDM4E (0.35) MAPTHCRTR1PTGER4KDM4EATM
SCHEMBL21192112 0.94 KDM4E (0.35) MAPTHCRTR1PTGER4KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389420-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-11-30 US disclosed
US-20230389420-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-11-30 US disclosed
US-11723270-B2 Organic optoelectronic diode and display device SAMSUNG SDI CO., LTD. (KR) 2023-08-08 US disclosed
US-11723270-B2 Organic optoelectronic diode and display device SAMSUNG SDI CO., LTD. (KR) 2023-08-08 US disclosed
US-11696498-B2 Compound for an organic optoelectronic device, organic optoelectronic device, and display device using the same SAMSUNG SDI CO., LTD. (KR) 2023-07-04 US disclosed
US-11696498-B2 Compound for an organic optoelectronic device, organic optoelectronic device, and display device using the same SAMSUNG SDI CO., LTD. (KR) 2023-07-04 US disclosed
US-20200161560-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2020-05-21 US disclosed
US-20200161563-A1 ORGANIC OPTOELECTRONIC DIODE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2020-05-21 US disclosed
US-20200127213-A1 COMOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2020-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11723270-B2 Organic optoelectronic diode and display device ITGB4, OR10J3, EPB41 MAPT 1598/4885HCRTR1 1113/4885PTGER4 290/4885
US-11696498-B2 Compound for an organic optoelectronic device, organic optoelectronic device, and display device using the same OR10J3, OCIAD1, OCIAD2 MAPT 2074/4885HCRTR1 233/4885PTGER4 2252/4885
US-20230389420-A1 ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE ITGB4, OR10J3, EPB41 MAPT 1732/4885HCRTR1 1281/4885PTGER4 237/4885
US-20200127213-A1 COMOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE USING THE SAME OR10J3, OCIAD1, OCIAD2 MAPT 2227/4885HCRTR1 275/4885PTGER4 2767/4885
US-20200161563-A1 ORGANIC OPTOELECTRONIC DIODE AND DISPLAY DEVICE ITGB4, OR10J3, EPB41 MAPT 1598/4885HCRTR1 1113/4885PTGER4 290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.