Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | TYR | P14679 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19433099 | 0.98 | PTGS2 (0.61) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL19433098 | 0.98 | PTGS2 (0.61) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL19433103 | 0.98 | PTGS2 (0.61) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL9743295 | 0.93 | HTT (0.72) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL16010537 | 0.88 | PTGS2 (0.55) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL31061257 | 0.88 | PTGS2 (0.55) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL30412261 | 0.86 | HTT (0.63) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL4653761 | 0.84 | HTT (0.61) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL4653586 | 0.84 | HTT (0.61) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL16432085 | 0.84 | HTT (0.61) | HTTNPC1HPGDMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118169263-A | Cell surface proteome in-situ analysis method based on interaction of host and guest and without calibration | 中国科学院大连化学物理研究所 | 2024-06-11 | — | — | CN | claimed |
| CN-117945877-A | Application of acyl phloroglucinol derivative in preparation of medicine or health care product for preventing and treating non-alcoholic steatohepatitis | 中国药科大学 | 2024-04-30 | — | — | CN | claimed |
| CN-116332742-A | Acyl phloroglucinol hetero-terpenoid compound and application thereof | 中国科学院昆明植物研究所 | 2023-06-27 | — | — | CN | claimed |
| CN-111170967-B | Acyl phloroglucinol derivatives, and pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2022-12-27 | — | — | CN | claimed |
| CN-112979600-B | Split-ring acyl phloroglucinol compounds and application thereof in preparation of anti-cancer drugs | 厦门大学 | 2022-11-08 | — | — | CN | claimed |
| CN-113461702-B | Acylphenol oligomer, preparation method and application thereof | 中国科学院昆明植物研究所 | 2022-06-21 | — | — | CN | claimed |
| CN-111233886-B | Dearylated isopentenyl acylated phloroglucinol heteroterpenoid compound and pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2022-06-17 | — | — | CN | claimed |
| CN-111056935-B | Dearomatized isopentenyl acyl phloroglucinol derivative, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2022-05-20 | — | — | CN | claimed |
| CN-114287425-A | Application of acylated phloroglucinol derivative in preparation of antibacterial drugs | 兰州大学 | 2022-04-08 | — | — | CN | claimed |
| CN-113461702-A | Acylphenol oligomer, preparation method and application thereof | 中国科学院昆明植物研究所 | 2021-10-01 | — | — | CN | claimed |
| US-20110021610-A1 | AROMATIC PRENYLTRANSFERASE FROM HOP | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2011-01-27 | — | — | US | claimed |
| US-7854946-B1 | Anti-inflammatory and anti-HIV compositions and methods of use | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-12-21 | — | — | US | claimed |
| WO-2009114939-A1 | AROMATIC PRENYLTRANSFERASE FROM HOP | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2009-09-24 | — | — | WO | claimed |
| US-20080269510-A1 | New alpha-glucosidase inhibitors and antibacterial compounds from Myrtus communis L. | INTERNATIONAL INSTITUTE OF CHEMICAL SCIENCES (PK) | 2008-10-30 | — | — | US | claimed |
| WO-2008071173-A1 | PREPARATIONS FOR INHIBITING PROSTAGLANDIN E2 SYNTHESIS | EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) | 2008-06-19 | — | — | WO | claimed |
| WO-2007060532-A2 | NOVEL THERAPEUTIC COMPOSITIONS AND METHOD FOR PRODUCING ACTIVE PRINCIPLES | R ET D PHARMA (MC) | 2007-05-31 | — | — | WO | claimed |
| EP-1112079-A1 | MYRTLE EXTRACT, PREPARATION METHOD AND USE | Pierre Fabre Dermo-Cosmetique (FR) | 2001-07-04 | — | — | EP | claimed |
| WO-2000016791-A1 | MYRTLE EXTRACT, PREPARATION METHOD AND USE | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2000-03-30 | — | — | WO | claimed |
| US-4101585-A | PRENYLATION OF ACYLPHLOROGLUCINOLS | CIBA-GEIGY CORPORATION (US) | 1978-07-18 | — | — | US | claimed |
| US-4053517-A | METHOD OF ACYLATION OF PHLOROGLUCINOL | ATLANTIC RESEARCH INSTITUTE LIMITED (BA) | 1977-10-11 | — | — | US | claimed |