Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230123 | 0.80 | EPHX2 (0.56) | TSHREPHX2EPHX1HTTKDM4E | |
| SCHEMBL15127321 | 0.80 | ACHE (0.51) | TSHRALDH1A1 | |
| SCHEMBL15267877 | 0.79 | EPHX1 (0.46) | EPHX2EPHX1 | |
| SCHEMBL15127323 | 0.78 | KMT2A (0.42) | TSHREPHX1KDM4EALDH1A1LMNA | |
| SCHEMBL24438211 | 0.78 | EPHX1 (0.67) | TSHREPHX2EPHX1 | |
| SCHEMBL28273620 | 0.78 | EGLN1 (0.40) | EPHX1ALDH1A1 | |
| SCHEMBL8279407 | 0.78 | KDM4E (0.50) | TSHREPHX1KDM4EALDH1A1 | |
| SCHEMBL16254542 | 0.77 | EPHX1 (0.56) | TSHREPHX2EPHX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11443515 | 0.77 | TSHR (0.64) | TSHREPHX2EPHX1HTTHPGD | |
| SCHEMBL16638256 | 0.76 | EPHX1 (0.57) | TSHREPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9329479-B2 | Lithographic printing plate precusor | AGFA GRAPHICS NV (BE) | 2016-05-03 | — | — | US | disclosed |
| US-20150168837-A1 | LITHOGRAPHIC PRINTING PLATE PRECUSOR | ECO3 BV (BE) | 2015-06-18 | — | — | US | disclosed |