SCHEMBL28273620

SCHEMBL28273620

CCO[SiH2]CCCNC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 1/20 0.40
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ACHE P22303 7/20 0.33
EPHX1 P07099 4/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15629698 0.85 ACHE (0.47) KMT2AACHEEPHX1
SCHEMBL8279407 0.85 KDM4E (0.50) CA12CA1CA2CA9MEN1
SCHEMBL17286268 0.83 EPHX1 (0.53) CA12CA1CA2CA9ACHE
SCHEMBL1770488 0.83 CA12 (0.34) EGLN1CA12CA1CA2CA9
SCHEMBL15127316 0.81 EPHX2 (0.40) EGLN1MEN1KMT2A
SCHEMBL13128990 0.80 ALDH1A1 (0.53) KMT2AALDH1A1
SCHEMBL16806560 0.79 ACHE (0.33) EGLN1CA12CA1CA2CA9
SCHEMBL16254540 0.78 ALOX15 (0.43) MEN1KMT2AACHEEPHX1
SCHEMBL16806509 0.78 TSHR (0.43) EPHX1ALDH1A1
SCHEMBL16254542 0.78 EPHX1 (0.56) EPHX1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109310616-A cosmetic composition for eye 株式会社资生堂 2019-02-05 CN claimed
CN-109310616-A cosmetic composition for eye 株式会社资生堂 2019-02-05 CN disclosed