SCHEMBL16807015

SCHEMBL16807015

N#Cc1ccc2c3cc(-c4nc(-c5ccc6ccccc6c5)nc(-c5ccc6ccccc6c5)n4)ccc3n(-c3ccccc3)c2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 6/20 0.40
PDPK1 O15530 1/20 0.37
CYP17A1 P05093 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
PTGER4 P35408 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
G6PD P11413 1/20 0.34
CYP1A2 P05177 4/20 0.34
MEN1 O00255 3/20 0.34
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 3/20 0.34
CYP3A4 P08684 3/20 0.34
LMNA P02545 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16809842 0.94 TDP2 (0.40) TDP2PDPK1CYP17A1CYP11B1CYP11B2
SCHEMBL16809801 0.94 TDP2 (0.40) TDP2PDPK1CYP17A1CYP11B1CYP11B2
SCHEMBL16807018 0.92 CYP1A2 (0.41) TDP2PTGER4KDM4EATML3MBTL1
SCHEMBL16809517 0.91 CYP17A1 (0.39) TDP2PDPK1CYP17A1CYP11B1CYP11B2
SCHEMBL16809812 0.88 PGR (0.36) TDP2PDPK1CYP17A1CYP11B1CYP11B2
SCHEMBL16456237 0.88 PDPK1 (0.37) TDP2PDPK1CYP17A1CYP11B1CYP11B2
SCHEMBL16809845 0.87 PDPK1 (0.39) TDP2PDPK1CYP17A1CYP11B1CYP11B2
SCHEMBL16809796 0.87 TDP2 (0.38) TDP2PDPK1CYP17A1CYP11B1CYP11B2
SCHEMBL16807017 0.87 TDP2 (0.38) TDP2PDPK1PTGER4KDM4EATM
SCHEMBL17032758 0.86 KDM4E (0.41) TDP2PTGER4KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9705088-B2 Triazine-based compounds and organic light-emitting devices including triazine-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-11 US disclosed
US-9705088-B2 Triazine-based compounds and organic light-emitting devices including triazine-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-11 US disclosed
US-20150171336-A1 TRIAZINE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES INCLUDING TRIAZINE-BASED COMPOUNDS SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US disclosed
US-20150171336-A1 TRIAZINE-BASED COMPOUNDS AND ORGANIC LIGHT-EMITTING DEVICES INCLUDING TRIAZINE-BASED COMPOUNDS SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-18 US disclosed