Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARG | P13631 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807076 | 0.94 | ALOX5 (0.45) | MCL1ALOX5GABRA1GABRB2CNR1 | |
| SCHEMBL16807110 | 0.92 | ALOX5 (0.51) | MCL1ALOX5GABRA1GABRB2CNR1 | |
| SCHEMBL15725328 | 0.92 | ALOX5 (0.46) | MCL1ALOX5GABRA1GABRB2CNR1 | |
| SCHEMBL16807140 | 0.92 | TSHR (0.40) | MCL1ALOX5RARBTSHRCYP4F2 | |
| SCHEMBL16807147 | 0.91 | RARB (0.50) | RARBRARARARGCA2 | |
| SCHEMBL16807142 | 0.91 | MCL1 (0.46) | MCL1ALOX5GABRA1GABRB2RARB | |
| SCHEMBL16807141 | 0.90 | MCL1 (0.48) | MCL1ALOX5GABRA1GABRB2CNR1 | |
| SCHEMBL15829720 | 0.89 | RARB (0.51) | RARBTSHRRARARARG | |
| SCHEMBL16807138 | 0.89 | RARB (0.45) | MCL1ALOX5RARBTSHRCYP4F2 | |
| SCHEMBL16807129 | 0.89 | FFAR1 (0.43) | MCL1RARBTSHRCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |