Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927526 | 0.93 | MEN1 (0.49) | KDM4EMAPTGAAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5566560 | 0.92 | MEN1 (0.48) | KDM4EMAPTGAAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7739976 | 0.91 | KDM4E (0.50) | KDM4EMAPTGAAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7739978 | 0.90 | KDM4E (0.49) | KDM4EMAPTGAAALDH1A1KMT2A | |
| SCHEMBL15567879 | 0.86 | KDM4E (0.55) | KDM4EMAPTGAAALDH1A1KMT2A | |
| SCHEMBL15568107 | 0.85 | HTT (0.54) | KDM4EMAPTGAAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL15567299 | 0.83 | KDM4E (0.56) | KDM4EMAPTGAAALDH1A1KMT2A | |
| SCHEMBL15567508 | 0.82 | GAA (0.51) | KDM4EMAPTGAAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7741352 | 0.82 | KDM4E (0.44) | KDM4EMAPTGAAALDH1A1KMT2A | |
| SCHEMBL2928557 | 0.81 | GAA (0.57) | KDM4EMAPTGAAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| WO-2015086676-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2015-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | KRT18, VIM, SORD | KDM4E 2067/4885MAPT 29/4885GAA 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.