Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2927526 | 0.99 | MEN1 (0.49) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7739978 | 0.97 | KDM4E (0.49) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7739976 | 0.96 | KDM4E (0.50) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL16807231 | 0.92 | KDM4E (0.50) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL6150986 | 0.89 | GAA (0.55) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL2928557 | 0.88 | GAA (0.57) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7741352 | 0.87 | KDM4E (0.44) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL5567515 | 0.87 | HTT (0.53) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL2930520 | 0.85 | KDM4E (0.54) | MEN1ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL15567545 | 0.84 | KDM4E (0.53) | MEN1ALDH1A1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064252-B1 | OXIDATION DYEING COMPOSITIONS CONTAINING A CATIONIC COUPLING AGENT, NOVEL CATIONIC COUPLING AGENTS | OREAL (FR) | 2005-06-15 | — | — | EP | claimed |
| US-6419711-B1 | PHENOLIC COMPOUND COUPLER | L'OREAL (FR) | 2002-07-16 | — | — | US | claimed |
| US-7229479-B2 | Method of coloring porous material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |
| US-20060162095-A1 | Method of colouring porous material | CIBA SPECIALTY CHEMICALS CORP. | 2006-07-27 | — | — | US | disclosed |
| EP-1534226-A1 | METHOD OF COLOURING POROUS MATERIAL | Ciba SC Holding AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004019897-A1 | METHOD OF COLOURING POROUS MATERIAL | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-11 | — | — | WO | disclosed |
| US-6419711-B1 | PHENOLIC COMPOUND COUPLER | L'OREAL (FR) | 2002-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162095-A1 | Method of colouring porous material | ACR, HLA-C, TYR | MEN1 615/4885ALDH1A1 2989/4885KMT2A 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.