Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516397 | 0.88 | GAA (0.58) | GAAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL3279093 | 0.84 | TDP1 (0.61) | GAAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL8099817 | 0.82 | GAA (0.74) | GAAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL8134520 | 0.81 | ALDH1A1 (0.73) | GAAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL24584894 | 0.81 | ALDH1A1 (0.56) | GAAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL1357609 | 0.81 | ALDH1A1 (0.57) | GAAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL11227813 | 0.81 | TDP1 (0.56) | GAAKDM4EALDH1A1HTTMAPT | |
| Hydrochloric Acid SCHEMBL11224670 | 0.81 | ALDH1A1 (0.78) | GAAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL11218926 | 0.81 | GAA (0.71) | GAAKDM4EALDH1A1HTTMAPT | |
| SCHEMBL34160 | 0.81 | GAA (0.71) | GAAKDM4EALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2016-10-27 | — | — | US | disclosed |
| WO-2015086676-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | L'OREAL (FR) | 2015-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310383-A1 | METHOD FOR DYEING KERATINOUS SUBSTANCES STARTING FROM COLOURED OLIGOMERS AND/OR POLYMERS RESULTING FROM META-PHENYLENEDIAMINES, COMPOSITION AND DYEING AGENT | KRT18, VIM, SORD | GAA 4553/4885KDM4E 2067/4885ALDH1A1 1145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.