Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 16/20 | 0.80 |
| ▸ | DRD2 | P14416 | 9/20 | 0.80 |
| ▸ | DRD5 | P21918 | 5/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.80 |
| ▸ | HPGD | P15428 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.80 |
| ▸ | THPO | P40225 | 2/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.80 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.80 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.80 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.80 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.80 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.80 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.80 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10748648 | 0.95 | DRD1 (0.80) | DRD1DRD2DRD5KDM4EHPGD | |
| Bromide SCHEMBL10746790 | 0.93 | DRD1 (0.80) | DRD1DRD2DRD5KDM4EHPGD | |
| (R)-Skf-38393 SCHEMBL7941051 | 0.89 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD | |
| Skf-38393 SCHEMBL29389401 | 0.89 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD | |
| Skf-38393 SCHEMBL469578 | 0.89 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD | |
| Skf-38393 SCHEMBL3425787 | 0.87 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD | |
| (R)-Skf-38393 SCHEMBL7201583 | 0.87 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD | |
| Skf-38393 SCHEMBL1874365 | 0.87 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD | |
| (R)-Skf-38393 SCHEMBL7201396 | 0.87 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD | |
| Skf-38393 SCHEMBL29387587 | 0.87 | DRD1 (1.00) | DRD1DRD2DRD5KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9949983-B2 | Fused benzazepines for treatment of stuttering | PSYADON PHARMACEUTICALS, INC. (US) | 2018-04-24 | — | — | US | disclosed |
| US-20160271141-A1 | FUSED BENZAZEPINES FOR TREATMENT OF STUTTERING | Psyadon Pharmaceuticals ,Inc. | 2016-09-22 | — | — | US | disclosed |
| US-20150164911-A1 | Fused Benzazepines for Treatment of Tourette's Syndrome | HORIZON TECHNOLOGY FINANCE CORPORATION | 2015-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271141-A1 | FUSED BENZAZEPINES FOR TREATMENT OF STUTTERING | TACR1, AVPR1A, AVPR1B | DRD1 28/4885DRD2 9/4885DRD5 40/4885 |
| US-20150164911-A1 | Fused Benzazepines for Treatment of Tourette's Syndrome | COMT, SLC6A3, HTR3A | DRD1 30/4885DRD2 8/4885DRD5 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.