SCHEMBL16808909

SCHEMBL16808909

C#CCN(CC)CC(=C)c1ccccc1

nearest known ligand 0.89

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 15/20 0.67
MAOB P27338 15/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168233 0.84 MAOA (0.51) MAOAMAOB
SCHEMBL16808953 0.83 MAOB (0.60) MAOAMAOB
SCHEMBL16795846 0.80 MAOA (1.00) MAOAMAOB
SCHEMBL4691160 0.78 MAOA (0.53) MAOAMAOB
SCHEMBL9779064 0.77 KDM4E (0.46) MAOAMAOB
Sulfuric Acid SCHEMBL9223818 0.77 ALDH1A1 (0.46) MAOAMAOB
SCHEMBL16808949 0.73 MAOA (0.65) MAOAMAOB
SCHEMBL10629899 0.72 MAOA (0.64) MAOAMAOB
SCHEMBL8415451 0.71 MAOA (0.46) MAOAMAOB
SCHEMBL16808907 0.71 MAOA (0.71) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015087094-A1 NEW ARYLALKENYLPROPARGYLAMINE DERIVATIVES EXHIBITING NEUROPROTECTIVE ACTION FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES SEMMELWEIS EGYETEM (HU) 2015-06-18 WO disclosed