Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811087 | 1.00 | KDM4E (0.56) | KDM4EGRM4LMNASMN1; SMN2RAB9A | |
| SCHEMBL11138427 | 0.85 | KDM4E (0.66) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL29733596 | 0.84 | KDM4E (0.53) | KDM4EGRM4LMNASMN1; SMN2RAB9A | |
| SCHEMBL22807516 | 0.84 | KDM4E (0.53) | KDM4EGRM4LMNASMN1; SMN2RAB9A | |
| SCHEMBL9359315 | 0.83 | KDM4E (0.63) | KDM4ELMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3288850 | 0.83 | KDM4E (0.47) | KDM4EGRM4LMNASMN1; SMN2MEN1 | |
| SCHEMBL15916364 | 0.79 | LMNA (0.46) | KDM4EGRM4LMNASMN1; SMN2RAB9A | |
| SCHEMBL10549193 | 0.79 | KDM4E (0.44) | KDM4EGRM4LMNASMN1; SMN2RAB9A | |
| SCHEMBL9722803 | 0.79 | KDM4E (0.44) | KDM4EGRM4LMNASMN1; SMN2RAB9A | |
| SCHEMBL16613062 | 0.78 | KDM4E (0.47) | KDM4EGRM4LMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111527094-B | Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device | 学校法人关西学院 | 2024-03-26 | — | — | CN | disclosed |
| CN-111527094-A | Compound having boron as spiro atom and polymer compound thereof | 学校法人关西学院 | 2020-08-11 | — | — | CN | disclosed |
| CN-107011251-B | Synthesis method and application of 2- (2-chlorophenoxy) pyridine compound | 温州医科大学 | 2020-08-11 | — | — | CN | disclosed |
| US-7932272-B2 | Antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-0288810-B1 | HETEROCYCLIC NEOPHANE ANALOGS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-02 | — | — | EP | disclosed |
| EP-0288810-A1 | Heterocyclic neophane analogs, processes for their preparation and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105943-A1 | Novel antifungal agent containing heterocyclic compound | ERG28, DPM1, CYP51A1 | KDM4E 3245/4885GRM4 3693/4885LMNA 2208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.