Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16809866 | 0.87 | CYP2C19 (0.48) | L3MBTL1HTTPKMHTR6TSHR | |
| SCHEMBL260617 | 0.82 | L3MBTL1 (0.55) | L3MBTL1POLBALDH3A1HTTNOD1 | |
| SCHEMBL5268905 | 0.80 | L3MBTL1 (0.43) | L3MBTL1POLBALDH3A1HTTNOD1 | |
| SCHEMBL30752005 | 0.80 | L3MBTL1 (0.52) | L3MBTL1POLBALDH3A1HTTNOD1 | |
| SCHEMBL1356181 | 0.80 | L3MBTL1 (0.52) | L3MBTL1POLBALDH3A1HTTNOD1 | |
| SCHEMBL28622254 | 0.80 | L3MBTL1 (0.52) | L3MBTL1POLBALDH3A1HTTNOD1 | |
| SCHEMBL4075074 | 0.80 | L3MBTL1 (0.52) | L3MBTL1POLBALDH3A1HTTNOD1 | |
| SCHEMBL14427677 | 0.80 | L3MBTL1 (0.52) | L3MBTL1POLBALDH3A1HTTNOD1 | |
| SCHEMBL31409677 | 0.80 | L3MBTL1 (0.46) | L3MBTL1POLBALDH3A1HTTNOD1 | |
| SCHEMBL15428434 | 0.79 | L3MBTL1 (0.48) | L3MBTL1POLBALDH3A1HTTNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015089327-A1 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | BIOGEN IDEC MA INC. (US) | 2015-06-18 | — | — | WO | disclosed |