SCHEMBL1681010

SCHEMBL1681010

[O-][n+]1cccc2ccc3cccnc3c21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.54
CCR8 P51685 5/20 0.54
LMNA P02545 4/20 0.54
CCR5 P51681 3/20 0.54
KDM4E B2RXH2 3/20 0.54
MMP2 P08253 2/20 0.54
TSHR P16473 2/20 0.54
MAPT P10636 2/20 0.54
HTT P42858 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
CYP3A4 P08684 2/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
HSP90AA1 P07900 1/20 0.54
CYP2D6 P10635 1/20 0.54
MMP9 P14780 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
MMP8 P22894 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7897391 0.80 CYP3A4 (0.56) CCR1CCR8LMNACCR5KDM4E
SCHEMBL30150881 0.78 KDM4E (0.54) CCR1CCR8LMNACCR5KDM4E
SCHEMBL9318851 0.78 KDM4E (0.54) CCR1CCR8LMNACCR5KDM4E
SCHEMBL4429040 0.77 LMNA (0.48) CCR1CCR8LMNACCR5KDM4E
SCHEMBL5352485 0.77 MAPT (0.41) LMNAKDM4ETSHRMAPTHTT
Iodide SCHEMBL1498884 0.76 KDM4E (0.52) CCR1CCR8LMNACCR5KDM4E
SCHEMBL1571887 0.72 KDM4E (0.39) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL29354015 0.72 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL29367277 0.72 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E
Phenanthroline SCHEMBL8312 0.72 CCR1 (1.00) CCR1CCR8LMNACCR5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591354-B Production and preparation method of 4-hydroxy-1, 5-naphthyridine europium complex 兰州睿尔思新材料有限公司 2023-11-24 CN claimed
EP-3562799-B1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2023-08-23 EP claimed
CN-110099884-B Ethylene oligomerization process 切弗朗菲利浦化学公司 2022-03-15 CN claimed
US-10544070-B2 Ethylene oligomerization process CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2020-01-28 US claimed
EP-3562799-A1 ETHYLENE OLIGOMERIZATION PROCESSES Chevron Phillips Chemical Company LP (US) 2019-11-06 EP claimed
US-20190276377-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2019-09-12 US claimed
US-10407360-B2 Ethylene oligomerization processes CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2019-09-10 US claimed
CN-110099884-A Ethylene oligomerisation processes 切弗朗菲利浦化学公司 2019-08-06 CN claimed
US-20190194089-A1 Ethylene Oligomerization Processes CHEVRON PHILLIPS CHEMICAL COMPANY LP 2019-06-27 US claimed
WO-2018125826-A1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-07-05 WO claimed
WO-2004052979-A1 A THERMOPLASTIC LIGHT-TRANSFORMING COPOLYMER COMPOSITION USEFUL FOR SHIFTING OF ULTRAVIOLET RADIATION INTO RED SPECTRAL REGION AND A METHOD FOR PRODUCTION THEREOF POLYMASTER LTD. (IL) 2004-06-24 WO claimed
CN-117551117-A Recycling method of 4-hydroxy-1, 5-naphthyridine europium complex preparation mother solution 苏州睿尔思科技有限公司 2024-02-13 CN disclosed
CN-114591354-B Production and preparation method of 4-hydroxy-1, 5-naphthyridine europium complex 兰州睿尔思新材料有限公司 2023-11-24 CN disclosed
EP-3562799-B1 ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL CO LP (US) 2023-08-23 EP disclosed
CN-116606325-A 2-tert-butylimino-phenanthroline imine metal (II) complex and synthetic method and application thereof 北京化工大学 2023-08-18 CN disclosed
WO-2004052979-A1 A THERMOPLASTIC LIGHT-TRANSFORMING COPOLYMER COMPOSITION USEFUL FOR SHIFTING OF ULTRAVIOLET RADIATION INTO RED SPECTRAL REGION AND A METHOD FOR PRODUCTION THEREOF POLYMASTER LTD. (IL) 2004-06-24 WO disclosed
EP-1366113-A1 METAL-CONTAINING DENDRIMERS ISIS INNOVATION LIMITED (GB) 2003-12-03 EP disclosed
WO-2002066552-A1 METAL-CONTAINING DENDRIMERS ISIS INNOVATION LIMITED (GB) 2002-08-29 WO disclosed
EP-0108437-B1 PROCESS FOR THE PREPARATION OF ETHYLIDENE DIACETATE AND/OR ACETIC ACID ANHYDRIDE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-05-14 EP disclosed
EP-0108437-A1 Process for the preparation of ethylidene diacetate and/or acetic acid anhydride SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190276377-A1 Ethylene Oligomerization Processes NOD2, AP1M1, AP2M1 CCR1 2132/4885CCR8 686/4885LMNA 4627/4885
US-20190194089-A1 Ethylene Oligomerization Processes NOD2, AP1M1, AP2M1 CCR1 2132/4885CCR8 686/4885LMNA 4627/4885
US-10544070-B2 Ethylene oligomerization process NOD2, AP1M1, AP2M1 CCR1 2248/4885CCR8 771/4885LMNA 4657/4885
US-10407360-B2 Ethylene oligomerization processes NOD2, AP1M1, AP2M1 CCR1 2132/4885CCR8 686/4885LMNA 4627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.