Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.63 |
| ▸ | CRHBP | P24387 | 1/20 | 0.63 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18070719 | 0.83 | MAOB (0.71) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL1820821 | 0.83 | MAOB (0.73) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL5598204 | 0.83 | MAOB (0.73) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL18906024 | 0.82 | MAPT (0.70) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL16810263 | 0.81 | MAPT (0.73) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL1321556 | 0.80 | MAPT (0.75) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL1321557 | 0.80 | MAPT (0.75) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL5597968 | 0.79 | MAPT (0.74) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL979280 | 0.79 | MAPT (0.79) | MAOBMAPTRAB9AKMT2ALMNA | |
| SCHEMBL2053346 | 0.79 | MAPT (0.79) | MAOBMAPTRAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066398-B2 | Small molecule c-Myc inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-07-20 | — | — | US | disclosed |
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | SORRENTO THERAPEUTICS, INC. | 2016-09-15 | — | — | US | disclosed |
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | SORRENTO THERAPEUTICS, INC. | 2016-09-15 | — | — | US | disclosed |
| WO-2015089180-A1 | SMALL MOLECULE C-MYC INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264560-A1 | SMALL MOLECULE C-MYC INHIBITORS | MYC, MYCBP, MYCBP2 | MAOB 3957/4885MAPT 1202/4885RAB9A 2195/4885 |
| US-11066398-B2 | Small molecule c-Myc inhibitors | MYC, MYCBP, MYCBP2 | MAOB 3957/4885MAPT 1202/4885RAB9A 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.