Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | ACLY | P53396 | 6/20 | 0.45 |
| ▸ | CPT2 | P23786 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL424027 | 1.00 | ALDH1A1 (0.71) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL27808233 | 1.00 | ALDH1A1 (0.71) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL426349 | 1.00 | ALDH1A1 (0.71) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL426131 | 1.00 | ALDH1A1 (0.71) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL431228 | 1.00 | ALDH1A1 (0.71) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL30464701 | 1.00 | ALDH1A1 (0.71) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL8903778 | 0.98 | ALDH1A1 (0.68) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL2024217 | 0.98 | ALDH1A1 (0.68) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL10629086 | 0.98 | ALDH1A1 (0.68) | ALDH1A1ACLYCPT2LMNAHMGCR | |
| Citric Acid SCHEMBL27683192 | 0.96 | ALDH1A1 (0.65) | ALDH1A1ACLYCPT2LMNAHMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 883 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122030612-A | Shear-resistant slow-release microcapsule powder and preparation method and application thereof | 大连医诺生物股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| EP-4604743-A1 | FORMULATED FOOD PRODUCTS | VitaKey Inc. (US) | 2025-08-27 | — | — | EP | claimed |
| WO-2025105320-A1 | HARMFUL ORGANISM CONTROL AGENT COMPOSITION AND HARMFUL ORGANISM CONTROL METHOD | 日本曹達株式会社 | 2025-05-22 | — | — | WO | claimed |
| CN-119969502-A | Fermented preparation in feed production process and preparation process thereof | 北京都润科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119605996-A | Biphase gel loaded with natural antioxidants and preparation method and application thereof | 江南大学 | 2025-03-14 | — | — | CN | claimed |
| CN-118948808-A | Melobalin besylate oral film agent and preparation method thereof | 山东大学 | 2024-11-15 | — | — | CN | claimed |
| CN-116234554-B | Methods and compositions for skin microbiome normalization of sensitive skin | 威诺药妆私人有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-118878902-A | Environment-friendly anti-counterfeiting packaging material and manufacturing process thereof | 泉州金源包袋有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118290908-A | Biodegradable composite mulching film and preparation method thereof | 四川大学 | 2024-07-05 | — | — | CN | claimed |
| CN-118104763-A | Soft ice cream or soft ice cream slurry for reducing sugar and fat and preparation method thereof | 内蒙古伊利实业集团股份有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-101027035-A | Compositions for removing stains from tooth surfaces and methods of making and using the same | CADBURY ADAMS USA LLC (US) | 2007-08-29 | — | — | CN | claimed |
| CN-101027037-A | Tooth whitening compositions and delivery systems therefor | CADBURY ADAMS USA LLC (US) | 2007-08-29 | — | — | CN | claimed |
| CN-101027036-A | Tooth whitening compositions and delivery systems therefor | CADBURY ADAMS USA LLC (US) | 2007-08-29 | — | — | CN | claimed |
| CN-101023213-A | Rechargeable finishing agent for textile fibers and fabrics | SCHOELLER TEXTIL AG (CH) | 2007-08-22 | — | — | CN | claimed |
| US-20060257507-A1 | Herbal cough formulations and process for the preparation thereof | J.B. CHEMICALS & PHARMACEUTICALS, LTD. (IN) | 2006-11-16 | — | — | US | claimed |
| CN-1243481-C | Stain removing chewing gum and confectionery compositions, and methods of making and using the same | CADBURY ADAMS USA LLC (US) | 2006-03-01 | — | — | CN | claimed |
| CN-1404363-A | Stain removing chewing gum and confectionery compositions, and methods of making and using the same | WARNER LAMBERT CO (US) | 2003-03-19 | — | — | CN | claimed |
| EP-0737425-B1 | Oil-in-water emulsion containing lysophospholipo-proteins | ASAHI DENKA KOGYO KK (JP) | 2001-09-12 | — | — | EP | claimed |
| US-5456746-A | Gelatin containing ester of fatty acid and glycerol; reduces cracking, chipping, leakage of capsules | WARNER-LAMBERT COMPANY (US) | 1995-10-10 | — | — | US | claimed |
| EP-0600422-A1 | Hard film composition for capsules | WARNER-LAMBERT COMPANY (US) | 1994-06-08 | — | — | EP | claimed |