Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.44 |
| ▸ | CDK1 | P06493 | 3/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.44 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16812968 | 0.89 | CDK5 (0.46) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16812964 | 0.88 | CDK5 (0.47) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16796663 | 0.88 | CYP11B1 (0.43) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16813045 | 0.86 | GSK3B (0.49) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16813035 | 0.81 | HPGD (0.47) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16812975 | 0.77 | GSK3B (0.45) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16812973 | 0.76 | CDK5 (0.39) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16813044 | 0.74 | CDK5 (0.49) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16813039 | 0.73 | CDK5 (0.50) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16796624 | 0.73 | CYP11B1 (0.53) | GSK3BCDK5CDK5R1GSK3ACCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088565-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |