Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 5/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | CCNT2 | O60583 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796663 | 0.88 | CYP11B1 (0.43) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16812964 | 0.86 | CDK5 (0.47) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16813043 | 0.83 | IMPDH2 (0.46) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16813029 | 0.78 | CCNB2 (0.43) | CCNB2CDK1CCNB1CCNB3IMPDH2 | |
| SCHEMBL16812968 | 0.76 | CDK5 (0.46) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16812972 | 0.76 | GSK3B (0.46) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16812974 | 0.72 | SMN1; SMN2 (0.44) | CDK5CDK5R1MAPK14IMPDH2PARP1 | |
| SCHEMBL16796624 | 0.71 | CYP11B1 (0.53) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16813039 | 0.69 | CDK5 (0.50) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16796639 | 0.67 | MMP2 (0.43) | CCNB2CDK1CCNB1CCNB3FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088565-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |