Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16813036 | 0.88 | CNR1 (0.56) | GSK3BCDK5CDK5R1GSK3ACNR1 | |
| SCHEMBL16796687 | 0.87 | CYP11B1 (0.48) | CNR1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL16812976 | 0.84 | GSK3B (0.40) | GSK3BCDK5CDK5R1GSK3ACNR1 | |
| SCHEMBL16796669 | 0.83 | CNR1 (0.43) | GSK3BCDK5CDK5R1GSK3ACNR1 | |
| SCHEMBL16813014 | 0.81 | CHRM4 (0.51) | GSK3BCNR1NTSR1OPRK1PDE4D | |
| SCHEMBL16813045 | 0.80 | GSK3B (0.49) | GSK3BCDK5CDK5R1GSK3ACCNB2 | |
| SCHEMBL16796592 | 0.80 | PTGS2 (0.49) | GSK3BCDK5CDK5R1GSK3ACNR1 | |
| SCHEMBL16813038 | 0.79 | CNR1 (0.56) | CNR1NTSR1OPRK1PDE4DNPSR1 | |
| SCHEMBL16812983 | 0.79 | CNR1 (0.47) | GSK3BGSK3ACNR1NTSR1OPRK1 | |
| SCHEMBL16813015 | 0.77 | LMNA (0.60) | GSK3BCDK5CDK5R1GSK3ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088565-A1 | P2X4 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2015-06-18 | — | — | WO | disclosed |