SCHEMBL16814866

SCHEMBL16814866

CP(=O)(O)OCCCCCCSSCCCCCCOP(C)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SAT1 P21673 1/20 0.46
▸ LPAR3 Q9UBY5 10/20 0.45
▸ LPAR2 Q9HBW0 9/20 0.45
▸ LPAR1 Q92633 4/20 0.45
▸ ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12662968 0.94 ALDH1A1 (0.42) SAT1LPAR3LPAR2LPAR1ALDH1A1
SCHEMBL21553512 0.93 SAT1 (0.41) SAT1LPAR3LPAR2LPAR1
SCHEMBL16815002 0.87 LPAR3 (0.56) SAT1LPAR3LPAR2LPAR1ALDH1A1
SCHEMBL16815019 0.87 LPAR3 (0.56) SAT1LPAR3LPAR2LPAR1ALDH1A1
SCHEMBL16815020 0.87 LPAR3 (0.56) SAT1LPAR3LPAR2LPAR1ALDH1A1
SCHEMBL16919757 0.86 SAT1 (0.44) SAT1LPAR3LPAR2LPAR1ALDH1A1
SCHEMBL12914742 0.84 SAT1 (0.57) SAT1LPAR3LPAR2LPAR1ALDH1A1
SCHEMBL17309416 0.81 SAT1 (0.33) SAT1LPAR3LPAR2LPAR1
SCHEMBL16919756 0.80 ALDH1A1 (0.52) SAT1LPAR3LPAR2LPAR1ALDH1A1
SCHEMBL13117333 0.80 LPAR3 (0.68) SAT1LPAR3LPAR2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11821026-B2 Chemical compositions and methods of using same NANOSTRING TECHNOLOGIES, INC. (US) 2023-11-21 — — US disclosed
US-20230366012-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING THE SAME BRUKER SPATIAL BIOLOGY, INC. 2023-11-16 — — US disclosed
US-20230220461-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2023-07-13 — — US disclosed
US-20180142286-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2018-05-24 — — US disclosed
US-9783804-B2 Compositions and methods for inhibition of nucleic acids function Life Technologies Corporation (US) 2017-10-10 — — US disclosed
US-20170009232-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION Life Technologies Corporation 2017-01-12 — — US disclosed
US-9410153-B2 Compositions and methods for inhibition of nucleic acids function Life Technologies Corporation (US) 2016-08-09 — — US disclosed
US-9145556-B2 Compositions and methods for inhibition of nucleic acids function Life Technologies Corporation (US) 2015-09-29 — — US disclosed
US-20150166992-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION Life Technologies Corporation (US) 2015-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170009232-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION RNGTT, NSUN3, NSUN2 SAT1 2634/4885LPAR3 1002/4885LPAR2 1486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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