Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4414140 | 1.00 | SLC6A12 (0.35) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL15700782 | 0.86 | EPHX1 (0.38) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL16815135 | 0.80 | MIF (0.36) | ALDH1A1POLBCYP1A2HPGD | |
| SCHEMBL15136255 | 0.78 | EPHX1 (0.40) | EPHX1 | |
| SCHEMBL10211021 | 0.78 | SLC6A12 (0.37) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL16815159 | 0.78 | SLC6A12 (0.37) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL17294479 | 0.78 | SLC6A12 (0.37) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL15700783 | 0.76 | SLC6A12 (0.38) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL5066828 | 0.75 | INPP5A (0.46) | EPHX1 | |
| SCHEMBL3375533 | 0.74 | SLC6A12 (0.42) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015088817-A1 | 4,4'-BIPHENYLDIYL-BIS-(1 H-IMIDAZOLYL) DERIVATIVES AS HEPATITIS HCV INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-06-18 | — | — | WO | disclosed |