Allylbenzene

Allylbenzene

SCHEMBL1681576

C=CCc1ccccc1.O=S(=O)(O)O.[NaH]

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Allylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB known ✓ P27338 1/20 0.44
CNR2 P34972 1/20 0.49
CYP3A4 P08684 3/20 0.44
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
BLM P54132 1/20 0.44
GFER P55789 1/20 0.44
PMP22 Q01453 1/20 0.44
CYP2C8 P10632 3/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 2/20 0.40
AKR1C3 P42330 1/20 0.40
AKR1C2 P52895 1/20 0.40
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
XDH P47989 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Allylbenzene SCHEMBL11301260 0.98 CNR2 (0.50) CNR2MAOBCYP3A4ALDH1A1KDM4E
Allylbenzene SCHEMBL44762 0.98 CNR2 (0.50) CNR2MAOBCYP3A4ALDH1A1KDM4E
Allylbenzene SCHEMBL18040305 0.96 CNR2 (0.49) CNR2MAOBCYP3A4ALDH1A1KDM4E
Allylbenzene SCHEMBL18040306 0.96 CNR2 (0.49) CNR2MAOBCYP3A4ALDH1A1KDM4E
Allylbenzene SCHEMBL28108484 0.90 CNR2 (0.46) CNR2MAOBCYP3A4ALDH1A1KDM4E
Allylbenzene SCHEMBL27290284 0.90 CNR2 (0.51) CNR2MAOBCYP3A4ALDH1A1KDM4E
Allylbenzene SCHEMBL27481287 0.87 MAOB (0.48) CNR2MAOBCYP3A4ALDH1A1CYP2C19
Allylbenzene SCHEMBL249313 0.87 MAOB (0.57) CNR2MAOBCYP3A4ALDH1A1KDM4E
Allylbenzene SCHEMBL318129 0.87 MAOB (0.57) CNR2MAOBCYP3A4ALDH1A1KDM4E
Allylbenzene SCHEMBL27636637 0.87 MAOB (0.57) CNR2MAOBCYP3A4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730769-A Ammonium chloride anti-caking agent 安徽天膜科技有限公司 2023-09-12 CN claimed
CN-114149871-A Biological environment-friendly oil stain cleaning agent with fire extinguishing function and preparation method and application thereof 南京军科超材科技有限公司 2022-03-08 CN claimed
US-11046922-B1 2-in-1 unit dose providing softening and detergency Henkel IP & Holding GmbH (DE) 2021-06-29 US claimed
US-20210179982-A1 2-in-1 Unit Dose Providing Softening And Detergency Henkel IP & Holding GmbH (DE) 2021-06-17 US claimed
CN-112608718-A Anti-slip agent 郑州聚砼汇实业有限公司 2021-04-06 CN claimed
US-10806143-B2 Herbicidal composition in granular form FMC CORPORATION (US) 2020-10-20 US claimed
CN-111100227-A Propylene polymerization method and device 中国石油化工股份有限公司 2020-05-05 CN claimed
CN-108203579-B Nitrogen foam gel plugging agent and preparation method and application thereof 中国石油天然气股份有限公司 2020-03-10 CN claimed
CN-1243075-C Negative pressure well fluid for oil well repairing operation and its prepn UNIV SHANDONG (CN) 2006-02-22 CN claimed
EP-1241649-B1 Composition for use in the testing of smoke detectors NO CLIMB PRODUCTS LTD (GB) 2005-05-11 EP claimed
CN-1526788-A Negative pressure well fluid for oil well repairing operation and its prepn 山东师范大学 2004-09-08 CN claimed
CN-1480517-A Carbon remover without need of disassembling engine 吴燕琳 2004-03-10 CN claimed
EP-1241649-A2 Composition for use in the testing of smoke detectors No Climb Products Limited (GB) 2002-09-18 EP claimed
EP-0530708-B1 Liquid laundry detergent compositions ALBRIGHT & WILSON UK LTD (GB) 1997-01-22 EP claimed
EP-3544581-B1 AQUEOUS COSMETIC LVMH RECH (FR) 2023-11-08 EP disclosed
US-20230338266-A1 AQUEOUS COSMETIC LVMH RECH (FR) 2023-10-26 US disclosed
CN-116730769-A Ammonium chloride anti-caking agent 安徽天膜科技有限公司 2023-09-12 CN disclosed
US-5053159-A phenoxy ethanol as antibacterial agent COLGATE-PALMOLIVE COMPANY (US) 1991-10-01 US disclosed
US-4729940-A Method of manufacturing master for optical information carrier CBS INC. (US) 1988-03-08 US disclosed
US-3935868-A Hair setting process THE PROCTER & GAMBLE COMPANY (US) 1976-02-03 US disclosed