Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Allylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allylbenzene SCHEMBL11301260 | 1.00 | CNR2 (0.50) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL1681576 | 0.98 | CNR2 (0.49) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL18040306 | 0.98 | CNR2 (0.49) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL18040305 | 0.98 | CNR2 (0.49) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL28108484 | 0.92 | CNR2 (0.46) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL27290284 | 0.92 | CNR2 (0.51) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL27636637 | 0.89 | MAOB (0.57) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL318129 | 0.89 | MAOB (0.57) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL5983821 | 0.88 | CNR2 (0.46) | CNR2MAOBCYP3A4ALDH1A1KDM4E | |
| Allylbenzene SCHEMBL27464808 | 0.88 | CNR2 (0.49) | CNR2MAOBCYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 833 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117339502-A | Preparation method of cool feeling microcapsule, cool feeling polyester fiber fabric and production method thereof | 罗莱生活科技股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117070288-A | Plastic cleaning agent and process for cleaning and recycling waste plastic by using same | 广东隽诺环保新材料有限公司 | 2023-11-17 | — | — | CN | claimed |
| US-11518964-B2 | LAS-containing cleaning agents with synergistically acting proteases and amylases | HENKEL AG & CO. KGAA (DE) | 2022-12-06 | — | — | US | claimed |
| CN-115418281-A | Self-structuring detergent composition | 广州蓝月亮实业有限公司 | 2022-12-02 | — | — | CN | claimed |
| CN-115321906-A | Graphite tailing foam concrete and preparation method thereof | 山东高速明董公路有限公司 | 2022-11-11 | — | — | CN | claimed |
| EP-4013453-A1 | HYDROPHOBIC PEPTIDE SALTS FOR EXTENDED RELEASE COMPOSITIONS | BioMarin Pharmaceutical Inc. (US) | 2022-06-22 | — | — | EP | claimed |
| US-20220186071-A1 | HEAT-SENSITIVE AQUEOUS POLYURETHANE DISPERSION AND METHOD FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-06-16 | — | — | US | claimed |
| EP-3980502-A1 | HEAT-SENSITIVE AQUEOUS POLYURETHANE DISPERSION AND METHOD FOR PREPARING THE SAME | Dow Global Technologies LLC (US) | 2022-04-13 | — | — | EP | claimed |
| CN-112430005-B | Cement admixture for inhibiting alkali aggregate reaction and preparation method thereof | 中建商品混凝土有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-109576097-B | Concentrated liquid detergent composition | 广州立白企业集团有限公司 | 2021-08-27 | — | — | CN | claimed |
| US-4760025-A | Modified enzymes and methods for making same | GENENCOR, INC. (US) | 1988-07-26 | — | — | US | claimed |
| EP-0266199-A2 | Liquid cleaning products | UNILEVER PLC (GB) | 1988-05-04 | — | — | EP | claimed |
| US-4731485-A | Process for hydroformylation with rhodium catalysts and the separation of rhodium therefrom | RUHRCHEMIE AKTIENGESELLSCHAFT (DE) | 1988-03-15 | — | — | US | claimed |
| EP-0232153-A2 | Detergent compositions | UNILEVER PLC (GB) | 1987-08-12 | — | — | EP | claimed |
| EP-0170091-A1 | Liquid detergent compositions | Albright & Wilson Limited (GB) | 1986-02-05 | — | — | EP | claimed |
| US-4430271-A | NEUTRALIZATION OF UNREACTED SULFATING AGENT USING HEAT EXCHANGING | PROCTER & GAMBLE COMPANY, A CORP. OF OHIO | 1984-02-07 | — | — | US | claimed |
| US-4153625-A | Neutralization process | BARTON BRANDON H | 1979-05-08 | — | — | US | claimed |
| US-4129516-A | SOAP USED AS A DRYING AGENT | THE PROCTER & GAMBLE COMPANY (US) | 1978-12-12 | — | — | US | claimed |
| US-4094804-A | FERROMAGNETIC OXIDE PARTICLES COATED WITH MONOMOLECULAR LAYER OF FATTY ACID AND AN OUTER LAYER OF NONIONIC OR ANIONIC SURFACTANT | SHIMOIIZAKA JUNZO | 1978-06-13 | — | — | US | claimed |
| US-3951825-A | ORGANIC ESTERS | EASTMAN KODAK COMPANY (US) | 1976-04-20 | — | — | US | claimed |