SCHEMBL16817596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28510190	1.00	FKBP1A (0.43)	FKBP1ALTA4HKLK5POLBADRA1D
	SCHEMBL19022219	0.85	HSD17B10 (0.47)	LTA4HPEPDHRH3SMN1; SMN2HSD17B10
	SCHEMBL1912615	0.85	HSD17B10 (0.47)	LTA4HPEPDHRH3SMN1; SMN2HSD17B10
	SCHEMBL16817598	0.84	HSD17B10 (0.46)	LTA4HPEPDHRH3SMN1; SMN2HSD17B10
	Lithium Ion SCHEMBL16817597	0.82	HRH3 (0.38)	HRH3SMN1; SMN2HSD17B10ALDH1A1LMNA
	SCHEMBL933205	0.80	LTA4H (0.48)	FKBP1ALTA4HPOLBADRA1DADRA1A
	SCHEMBL3706911	0.80	LTA4H (0.48)	FKBP1ALTA4HPOLBADRA1DADRA1A
	SCHEMBL28510170	0.79	PEPD (0.41)	FKBP1ALTA4HPOLBADRA1DADRA1A
	SCHEMBL12788427	0.78	FKBP1A (0.47)	FKBP1ALTA4HPOLBADRA1DADRA1A
	SCHEMBL16480466	0.78	HRH3 (0.48)	HRH3SMN1; SMN2ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.