SCHEMBL16817841

SCHEMBL16817841

O=C(c1ccccc1)c1cccc(-c2ccccn2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
KAT6A Q92794 2/20 0.56
KMT2A Q03164 2/20 0.55
KDM4E B2RXH2 2/20 0.53
KDM6B O15054 1/20 0.53
KDM4A O75164 1/20 0.53
KDM5C P41229 1/20 0.53
KDM4C Q9H3R0 1/20 0.53
KDM2A Q9Y2K7 1/20 0.53
KDM3A Q9Y4C1 1/20 0.53
ALDH1A1 P00352 2/20 0.50
CYP2A6 P11509 1/20 0.50
PBRM1 Q86U86 1/20 0.50
CNR1 P21554 1/20 0.50
MEN1 O00255 1/20 0.50
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
FFAR1 O14842 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5108635 0.96 KAT6A (0.55) ATMTDP1L3MBTL1KAT6AKMT2A
SCHEMBL12551797 0.88 KAT6A (0.51) KAT6AKMT2AKDM4EKDM6BKDM4A
SCHEMBL207017 0.87 KDM4E (0.69) KAT6AKDM4EKDM6BKDM4AKDM5C
SCHEMBL29800516 0.87 KDM4E (0.69) KAT6AKDM4EKDM6BKDM4AKDM5C
SCHEMBL16108931 0.86 KAT6A (0.56) KAT6AKMT2AKDM4EKDM6BKDM4A
SCHEMBL12551728 0.85 KDM4E (0.51) TDP1KAT6AKMT2AKDM4EKDM6B
SCHEMBL13326879 0.85 KMT2A (0.58) KMT2AKDM4EKDM6BKDM4AKDM5C
SCHEMBL2457556 0.84 KAT6A (0.54) TDP1L3MBTL1KAT6AKMT2AKDM4E
SCHEMBL13112159 0.84 KMT2A (0.58) KMT2AKDM4EKDM6BKDM4AKDM5C
SCHEMBL27605053 0.83 SLC6A7 (0.55) KMT2AKDM4ECYP2A6MEN1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150179961-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-25 US disclosed
US-20150179961-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-25 US disclosed
US-20150179961-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150179961-A1 ORGANIC ELECTROLUMINESCENCE MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME L1CAM, PIEZO1, OR10J3 ATM 3064/4885TDP1 2087/4885L3MBTL1 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.