Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1681887 | 0.99 | MEN1 (0.57) | NPC1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8132361 | 0.95 | MEN1 (0.55) | NPC1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1681984 | 0.86 | KMT2A (0.55) | NPC1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1681970 | 0.85 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL1809984 | 0.85 | KMT2A (0.54) | NPC1MEN1KMT2AALDH1A1KDM4E | |
| Bromide SCHEMBL1681744 | 0.84 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL1681816 | 0.84 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL1681956 | 0.83 | CCR3 (0.56) | ALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL1682096 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL1682022 | 0.82 | CCR3 (0.54) | ALDH1A1POLBHTTSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501778-B2 | Aralkyl piperidine derivatives and their uses as antalgic or ataractic agent | NHWA PHARMA. CORPORATION (CN) | 2013-08-06 | — | — | US | claimed |
| EP-2305645-B1 | ARALKYL PIPERIDINE DERIVATIVES AND THEIR USES AS ANTALGIC OR ATARACTIC AGENT | NHWA PHARMA CORP (CN) | 2012-05-16 | — | — | EP | claimed |
| US-20110105503-A1 | ARALKYL PIPERIDINE DERIVATIVES AND THEIR USES AS ANTALGIC OR ATARACTIC AGENT | NHWA PHARMA. CORPORATION (CN) | 2011-05-05 | — | — | US | claimed |
| EP-2305645-A1 | ARALKYL PIPERIDINE DERIVATIVES AND THEIR USES AS ANTALGIC OR ATARACTIC AGENT | NHWA Pharma.corporation (CN) | 2011-04-06 | — | — | EP | claimed |
| US-8501778-B2 | Aralkyl piperidine derivatives and their uses as antalgic or ataractic agent | NHWA PHARMA. CORPORATION (CN) | 2013-08-06 | — | — | US | disclosed |
| EP-2305645-B1 | ARALKYL PIPERIDINE DERIVATIVES AND THEIR USES AS ANTALGIC OR ATARACTIC AGENT | NHWA PHARMA CORP (CN) | 2012-05-16 | — | — | EP | disclosed |
| US-20110105503-A1 | ARALKYL PIPERIDINE DERIVATIVES AND THEIR USES AS ANTALGIC OR ATARACTIC AGENT | NHWA PHARMA. CORPORATION (CN) | 2011-05-05 | — | — | US | disclosed |
| EP-2305645-A1 | ARALKYL PIPERIDINE DERIVATIVES AND THEIR USES AS ANTALGIC OR ATARACTIC AGENT | NHWA Pharma.corporation (CN) | 2011-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105503-A1 | ARALKYL PIPERIDINE DERIVATIVES AND THEIR USES AS ANTALGIC OR ATARACTIC AGENT | ADK, AAK1, ATAD5 | NPC1 3505/4885MEN1 4294/4885KMT2A 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.