Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682267 | 0.89 | ALDH1A1 (0.52) | CNR2ALDH1A1SMN1; SMN2NPSR1KCNH2 | |
| SCHEMBL1682295 | 0.88 | CNR2 (0.52) | CNR2CNR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL1682259 | 0.88 | ALDH1A1 (0.52) | CNR2CNR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL1682316 | 0.88 | HTR2A (0.57) | CNR2CNR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL1682266 | 0.86 | ALDH1A1 (0.50) | CNR2CNR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL1682261 | 0.86 | CNR2 (0.55) | CNR2CNR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL1682301 | 0.83 | CNR2 (0.60) | CNR2CNR1ALDH1A1RORCTHRB | |
| SCHEMBL1682452 | 0.83 | ALDH1A1 (0.47) | CNR2ALDH1A1SMN1; SMN2NPSR1HRH3 | |
| SCHEMBL1682331 | 0.83 | CNR2 (0.53) | CNR2CNR1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL1682332 | 0.77 | TAS2R14 (0.49) | CNR2CNR1ALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043519-A2 | SULFONAMIDE DERIVATIVES AS SEROTONIN RECEPTOR ANTAGONIST AND SEROTONIN REUPTAKE INHIBITOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-14 | — | — | WO | claimed |
| WO-2011043519-A2 | SULFONAMIDE DERIVATIVES AS SEROTONIN RECEPTOR ANTAGONIST AND SEROTONIN REUPTAKE INHIBITOR | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2011-04-14 | — | — | WO | disclosed |