Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16558839 | 1.00 | L3MBTL1 (0.37) | L3MBTL1CYP2C9CYP2C19IDO1TDO2 | |
| SCHEMBL4368185 | 0.79 | GNAI3 (0.36) | — | |
| SCHEMBL15372476 | 0.79 | GNAI3 (0.36) | — | |
| SCHEMBL13355756 | 0.79 | SAT1 (0.36) | IDO1TDO2 | |
| SCHEMBL10867271 | 0.77 | CYP2D6 (0.44) | IDO1TDO2 | |
| SCHEMBL19415302 | 0.76 | IDO1 (0.35) | IDO1TDO2 | |
| SCHEMBL5046593 | 0.76 | IKBKB (0.34) | IDO1TDO2 | |
| SCHEMBL13694051 | 0.75 | DPP4 (0.35) | IDO1TDO2 | |
| SCHEMBL25555110 | 0.75 | CYP2D6 (0.33) | IDO1TDO2 | |
| SCHEMBL9550018 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409855-B2 | Asymmetric synthesis of (−)-venlafaxine using organocatalyst | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-09 | — | — | US | claimed |
| US-20150175524-A1 | ASYMMETRIC SYNTHESIS OF (-)-VENLAFAXINE USING ORGANOCATALYST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-06-25 | — | — | US | claimed |
| US-9409855-B2 | Asymmetric synthesis of (−)-venlafaxine using organocatalyst | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-09 | — | — | US | disclosed |
| US-20150175524-A1 | ASYMMETRIC SYNTHESIS OF (-)-VENLAFAXINE USING ORGANOCATALYST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-06-25 | — | — | US | disclosed |