Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16823350 | 1.00 | METTL3 (0.53) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL1045788 | 0.93 | METTL3 (0.57) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL1045787 | 0.93 | METTL3 (0.57) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL1079181 | 0.90 | METTL3 (0.55) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL1079178 | 0.90 | METTL3 (0.55) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL1043619 | 0.89 | METTL3 (0.58) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL4361111 | 0.86 | METTL3 (0.54) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL1045686 | 0.86 | METTL3 (0.57) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL4376148 | 0.86 | METTL3 (0.55) | METTL3TOP1GAAHTTNOTUM | |
| SCHEMBL1045688 | 0.86 | METTL3 (0.57) | METTL3TOP1GAAHTTNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150174117-A1 | 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS PHARMACEUTICAL AGENT | JAPAN TOBACCO INC. | 2015-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150174117-A1 | 4-OXOQUINOLINE COMPOUND AND USE THEREOF AS PHARMACEUTICAL AGENT | IMPDH1, CDKL4, IMPDH2 | METTL3 1398/4885TOP1 303/4885GAA 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.