Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16824120 | 0.94 | MEN1 (0.40) | SLC6A4MAP3K14MEN1KMT2AHTR6 | |
| SCHEMBL16824114 | 0.84 | MEN1 (0.42) | SLC6A4MAP3K14MEN1KMT2AHTR6 | |
| SCHEMBL17242239 | 0.84 | POLB (0.45) | SLC6A4MAP3K14MEN1KMT2AHTR6 | |
| SCHEMBL16824126 | 0.83 | MAPT (0.50) | SLC6A4MAP3K14MEN1KMT2AHTR6 | |
| SCHEMBL17242293 | 0.83 | MAOA (0.44) | MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL16824131 | 0.82 | HTR6 (0.41) | SLC6A4MAP3K14MEN1KMT2AHTR6 | |
| SCHEMBL16824118 | 0.78 | MAPT (0.49) | SLC6A4MAP3K14MEN1KMT2AHTR6 | |
| SCHEMBL16824134 | 0.78 | MEN1 (0.41) | SLC6A4MEN1KMT2AHTR6KDM4E | |
| SCHEMBL17242109 | 0.78 | POLB (0.43) | SLC6A4MAP3K14MEN1KMT2AHTR6 | |
| SCHEMBL17242424 | 0.77 | MAOA (0.42) | MEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016192657-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS OF USE AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-12-08 | — | — | WO | disclosed |
| EP-3083589-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS OF USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015169180-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-11-12 | — | — | WO | disclosed |
| WO-2015090235-A1 | SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS OF USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-06-25 | — | — | WO | disclosed |