Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CCR3 | P51677 | 7/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453749 | 0.86 | ACHE (0.56) | MEN1KMT2A | |
| SCHEMBL1581690 | 0.86 | ACHE (0.56) | MEN1KMT2A | |
| SCHEMBL2925616 | 0.86 | MEN1 (0.60) | MEN1KMT2APOLBCYP2C9CYP2C19 | |
| SCHEMBL23365213 | 0.83 | CYP2C9 (0.54) | MEN1KMT2APOLBCYP2C9CYP2C19 | |
| SCHEMBL23327685 | 0.83 | CYP2C9 (0.52) | MEN1KMT2APOLBCCR3CYP2C9 | |
| SCHEMBL18280185 | 0.82 | GPR119 (0.49) | MEN1KMT2ACCR3 | |
| SCHEMBL23365206 | 0.82 | CYP2C9 (0.52) | MEN1KMT2APOLBCCR3CYP2C9 | |
| SCHEMBL19994627 | 0.81 | MEN1 (0.55) | MEN1KMT2APOLBCCR3CYP2C9 | |
| SCHEMBL23365142 | 0.78 | CCR3 (0.57) | MEN1KMT2ACCR3CYP2C9CYP2C19 | |
| SCHEMBL1872372 | 0.78 | CYP2C9 (0.49) | MEN1KMT2ACCR3CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083584-B1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN THE TREATMENT OF TISSUE FIBROSIS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2018-02-21 | — | — | EP | disclosed |
| EP-3083584-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | Sunshine Lake Pharma Co., Ltd. (CN) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015090232-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-06-25 | — | — | WO | disclosed |