Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | HTR7 | P34969 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825825 | 0.82 | THRB (0.49) | ADORA3ADORA2AADORA1KMT2APKM | |
| SCHEMBL16825779 | 0.79 | KDM4E (0.47) | DRD2HTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL16825978 | 0.78 | SIGMAR1 (0.52) | DRD2HTR7KMT2AUSP2MAPT | |
| SCHEMBL16825915 | 0.78 | SIGMAR1 (0.52) | DRD2HTR7KMT2AUSP2MAPT | |
| SCHEMBL16825923 | 0.78 | POLB (0.42) | MCHR1DRD2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16825916 | 0.78 | SIGMAR1 (0.52) | DRD2HTR7KMT2AUSP2MAPT | |
| SCHEMBL16825973 | 0.78 | POLB (0.42) | MCHR1DRD2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16825808 | 0.78 | POLB (0.42) | MCHR1DRD2ALDH1A1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL18129143 | 0.77 | SIGMAR1 (0.54) | DRD2KMT2AUSP2MAPT | |
| Hydrochloric Acid SCHEMBL18129142 | 0.77 | SIGMAR1 (0.54) | DRD2KMT2AUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | The Institute For Drug Delivery (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095701-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | THE INSTITUTE FOR DRUG DELIVERY (US) | 2015-06-25 | — | — | WO | disclosed |