Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 10/20 | 0.53 |
| ▸ | CHIT1 | Q13231 | 9/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | CHI3L1 | P36222 | 1/20 | 0.39 |
| ▸ | CHI3L2 | Q15782 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1242233 | 0.89 | TAAR1 (0.60) | CHIACHIT1TAAR1SIGMAR1GRIN2B | |
| SCHEMBL3581153 | 0.84 | GRIN2B (0.56) | CHIATAAR1SIGMAR1GRIN2BSLC6A2 | |
| SCHEMBL7464765 | 0.82 | GRIN2B (0.39) | CHIACHIT1GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL5650537 | 0.81 | GRIN2B (0.41) | CHIACHIT1GRIN2BSLC6A2SLC6A4 | |
| SCHEMBL548295 | 0.79 | SLC6A4 (0.52) | CHIACHIT1TAAR1SLC6A2SLC6A4 | |
| SCHEMBL3041474 | 0.79 | GRIN2B (0.45) | CHIAGRIN2BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23580210 | 0.76 | TACR1 (0.54) | TAAR1GRIN2BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27544721 | 0.75 | GRIN2B (0.58) | SIGMAR1GRIN2BSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29913509 | 0.75 | SLC6A4 (0.55) | CHIATAAR1SIGMAR1GRIN2BSLC6A2 | |
| SCHEMBL31016704 | 0.75 | SLC6A4 (0.55) | CHIATAAR1SIGMAR1GRIN2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-B1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INST FOR DRUG DISCOVERY LLC (US) | 2020-02-05 | — | — | EP | disclosed |
| EP-3082805-B1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INST FOR DRUG DISCOVERY LLC (US) | 2020-02-05 | — | — | EP | disclosed |
| EP-3082805-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | The Institute For Drug Delivery (US) | 2016-10-26 | — | — | EP | disclosed |
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
| WO-2015095701-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | THE INSTITUTE FOR DRUG DELIVERY (US) | 2015-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | CMA1, CHIA, AADAC | CHIA 2/4885CHIT1 11/4885TAAR1 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.